Part 11 (1/2)
In April, 1795, a general inoculation taking place here, Merret was inoculated with his family; so that a period of twenty-five years had elapsed froh the variolous matter was repeatedly inserted into his arm, I found it impracticable to infect hi on an erysipelatous look about the centre, appearing on the skin near the punctured parts During the whole time that his family had the smallpox, one of whom had it very full, he remained in the house with theion
It is necessary to observe that the utmost care was taken to ascertain, with the most scrupulous precision, that no one whose case is here adduced had gone through the smallpox previous to these attempts to produce that disease
Had these experihbourhood, soht have been entertained; but here, where population is thin, and where such an event as a person's having had the smallpox is always faithfully recorded, as risk of inaccuracy in this particular can arise
CASE II--Sarah Portlock, of this place, was infected with the cow-pox when a servant at a faro [Footnote: I have purposely selected several cases in which the disease had appeared at a very distant period previous to the experie produced in the constitution is not affected by ti herself, from this circumstance, secure from the infection of the smallpox, she nursed one of her own children who had accidentally caught the disease, but no indisposition ensued During the time she remained in the infected room, variolous matter was inserted into both her ar case
CASE III--John Phillips, a tradesman of this town, had the cow- pox at so early a period as nine years of age At the age of sixty-two I inoculated hi matter in its most active state It was taken from the arm of a boy just before the commencement of the eruptive fever, and instantly inserted It very speedily produced a sting-like feel in the part An efflorescence appeared, which on the fourth day was rather extensive, and soree of pain and stiffness were felt about the shoulder; but on the fifth day these syan to disappear, and in a day or two after went entirely off, without producing any effect on the systee, of Woodford, in this parish, was inoculated with variolous matter in the year 1791 An efflorescence of a palish red colour soon appeared about the parts where the matter was inserted, and spread itself rather extensively, but died away in a few days without producing any variolous symptoms
[Footnote: It is remarkable that variolous matter, when the system is disposed to reject it, should excite inflammation on the part to which it is applied more speedily than when it produces the smallpox Indeed, it becomes almost a criterion by which we can determine whether the infection will be received or not It seeh life, had been produced in the action, or disposition to action, in the vessels of the skin; and it is ree has been effected by the smallpox or the cow-pox that the disposition to sudden cuticular inflammation is the same on the application of variolous matter] She has since been repeatedly e any ill consequences This woman had the cow-pox when she lived in the service of a farmer in this parish thirty-one years before
CASE V--Mrs H---, a respectable gentlewo She received the infection in rather an unco some of the same utensils [Footnote: When the cow-pox has prevailed in the dairy, it has often been communicated to those who have not milked the cows, by the handle of thethe servants of the fa infected cows Her hands had many of the cow-pox sores upon them, and they were communicated to her nose, which became inflamed and very much swollen Soon after this event Mrs H---- was exposed to the contagion of the smallpox, where it was scarcely possible for her to have escaped, had she been susceptible of it, as she regularly attended a relative who had the disease in so violent a degree that it proved fatal to him
In the year 1778 the smallpox prevailed veryperfectly satisfied respecting her safety (no indisposition having followed her exposure to the smallpox), I inoculated her with active variolouscases--an efflorescence on the arm without any effect on the constitution
CASE VI--It is a fact so well known a our dairy farmers that those who have had the smallpox either escape the cow-pox or are disposed to have it slightly, that as soon as the co the cattle, assistants are procured, if possible, who are thus rendered less susceptible of it, otherwise the business of the faro forward
In the month of May, 1796, the cow-pox broke out at Mr Baker's, a farmer who lives near this place The disease was communicated by means of a cohich was purchased in an infected state at a neighbouring fair, and not one of the far of thirty) which were at that tiion
The family consisted of a man servant, two dairymaids, and a servant boy, ith the far the cattle The whole of this faone through the smallpox The consequence was that the farmer and the servant boy escaped the infection of the cow-pox entirely, and the servanters, which produced no disorder in the system But the other dairymaid, Sarah Wynne, who never had the sht the complaint from the cows, and was affected with the syree that she was confined to her bed, and rendered incapable for several days of pursuing her ordinary vocations in the farirl and carefully rubbed the variolous ht incisions made upon the left arm A little inflammation appeared in the usual manner around the parts where the matter was inserted, but so early as the fifth day it vanished entirely without producing any effect on the syste history pretty clearly evinces that the constitution is far less susceptible of the contagion of the cow-pox after it has felt that of the seneral, as I have observed, they who have had the s cohich are infected with the cow- pox, either escape the disorder, or have sores on the hands without feeling any general indisposition, yet the animal economy is subject to so relation will point out:
In the summer of the year 1796 the cow-pox appeared at the far to the town of Berkeley It was co instance, by an infected cow purchased at a fair in the neighbourhood The family consisted of the farmer, his wife, two sons, a man and a maid servant; all of whom, except the farmer (as fearful of the consequences), bore a part inthe cows The whole of theh the smallpox; but in this case no one who ion All of theeneral indisposition, preceded by pains and tumours in the axillas: but there was no comparison in the severity of the disease as it was felt by the servant man, who had escaped the smallpox, and by those of the family who had not, for, while he was confined to his bed, they were able, without much inconvenience, to follow their ordinary business
February the 13th, 1797, I availedWilliam Rodway, the servant man above alluded to
Variolous ht, by ht punctures into the cutis Both were perceptibly inflamed on the third day After this the inflammation about the punctures soon died away, but a ses of the incisions till the eighth day, when a little uneasiness was felt for the space of half an hour in the right axilla The infla the most distant mark of affection of the systeed fifty-seven, lived as a servant with a neighbouring faro She was then a dairyht the disease with the rest of the faree, one very ser of her left hand, and scarcely any perceptible indisposition, following it
As the ht a manner, and as it had taken place at so distant a period of her life, I was happy with the opportunity of trying the effects of variolous matter upon her constitution, and on the 28th of March, 1797, I inoculated her bytwo superficial incisions on the left arm, on which the matter was cautiously rubbed A little efflorescence soon appeared, and a tingling sensation was felt about the parts where the an to subside, and so early as the fifth day it was evident that no indisposition would follow
CASE IX--Although the cow-pox shi+elds the constitution froainst its own future poison, yet it appears that the huain susceptible of the infectioushistory will demonstrate
William Smith, of Pyrton in this parish, contracted this disease when he lived with a neighbouring far to the farm had sore heels, and it fell to his lot to attend him By these means the infection was carried to the cows, and from the cows it was communicated to Smith On one of his hands were several ulcerated sores, and he was affected with such symptoms as have been before described
In the year 1791 the cow-pox broke out at another farm where he then lived as a servant, and he became affected with it a second time; and in the year 1794 he was so unfortunate as to catch it again The disease was equally as severe the second and third time as it was on the first [Footnote: This is not the case in general--a second attack is co the cows]
In the spring of the year 1795 he ice inoculated, but no affection of the system could be produced from the variolous matter; and he has since associated with those who had the s any effect from it
CASE X--Sientleman who resides on his own farm in this parish, in the year 1782 He was es to the sore heels of one of histhe cows The cows became affected in consequence, but the disease did not shew itself on their nipples till several weeks after he had begun to dress the horse He quitted Mr
Broe's service, and went to another faran to be affected in the common way, and he wasthe nature of thethere also e, the coas communicated to the cows
Some years afterward Nichols was employed in a farm where the smallpox broke out, when I inoculated hi the whole time of their confinement His ar with the inoculated family produced the least effect upon his constitution
CASE XI--Williae's farm at the time the cattle had the cow-pox, and he was, unfortunately, infected by them His left hand was very severely affected with several corroding ulcers, and a tumour of considerable size appeared in the axilla of that side His right hand had only one small tumour upon it, and no sore discovered itself in the corresponding axilla