Part 12 (2/2)

CCXIX

The great tragedy of Science--the slaying of a beautiful hypothesis by an ugly fact.

CCXX

It remains yet in the order of logic, though not of history, to show that among these solid destructible particles there really do exist germs capable of giving rise to the development of living forms in suitable menstrua. This piece of work was done by M. Pasteur in those beautiful researches which will ever render his name famous; and which, in spite of all attacks upon them, appear to me now, as they did seven years ago, to be models of accurate experimentation and logical reasoning. He strained air through cotton-wool, and found, as Schroeder and Dusch had done, that it contained nothing competent to give rise to the development of life in fluids highly fitted for that purpose. But the important further links in the chain of evidence added by Pasteur are three. In the first place he subjected to microscopic examination the cottonwool which had served as strainer, and found that sundry bodies clearly recognisable as germs were among the solid particles strained off. Secondly, he proved that these germs were competent to give rise to living forms by simply sowing them in a solution fitted for their development. And, thirdly, he showed that the incapacity of air strained through cotton-wool to give rise to life was not due to any occult change effected in the const.i.tuents of the air by the wool, by proving that the cotton-wool might be dispensed with altogether, and perfectly free access left between the exterior air and that in the experimental flask. If the neck of the flask is drawn out into a tube and bent downwards; and if, after the contained fluid has been carefully boiled, the tube is heated sufficiently to destroy any germs which may be present in the air which enters as the fluid cools, the apparatus may be left to itself for any time and no life will appear in the fluid.

The reason is plain. Although there is free communication between the atmosphere laden with germs and the germless air in the flask, contact between the two takes place only in the tube; and as the germs cannot fall upwards, and there are no currents, they never reach the interior of the flask. But if the tube be broken short off where it proceeds from the flask, and free access be thus given to germs falling vertically out of the air, the fluid, which has remained clear and desert for months, becomes, in a few days, turbid and full of life.

CCXXI

In autumn it is not uncommon to see flies motionless upon a window-pane, with a sort of magic circle, in white, drawn round them. On microscopic examination, the magic circle is found to consist of innumerable spores, which have been thrown off in all directions by a minute fungus called _Empusa museae_ the spore-forming filaments of which stand out like a pile of velvet from the body of the fly. These spore-forming filaments are connected with others which fill the interior of the fly's body like so much fine wool, having eaten away and destroyed the creature's viscera. This is the full-grown condition of the _Empusa_. If traced back to its earliest stages, in flies which are still active, and to all appearance healthy, it is found to exist in the form of minute corpuscles which float in the blood of the fly. These multiply and lengthen into filaments, at the expense of the fly's substance; and when they have at last killed the patient, they grow out of its body and give off spores. Healthy flies shut up with diseased ones catch this mortal disease, and perish like the others. A most competent observer, M. Cohn, who studied the development of the _Empusa_ very carefully, was utterly unable to discover in what manner the smallest germs of the _Empusa_ got into the fly. The spores could not be made to give rise to such germs by cultivation; nor were such germs discoverable in the air, or in the food of the fly. It looked exceedingly like a case of Abiogenesis, or, at any rate, of Xenogenesis; and it is only quite recently that the real course of events has been made out. It has been ascertained that when one of the spores falls upon the body of a fly, it begins to germinate, and sends out a process which bores its way through the fly's skin; this, having reached the interior cavities of its body, gives off the minute floating corpuscles which are the earliest stage of the _Empusa_. The disease is ”contagious”, because a healthy fly coming in contact with a diseased one, from which the spore-bearing filaments protrude, is pretty sure to carry off a spore or two. It is ”infectious” because the spores become scattered about all sorts of matter m the neighbourhood of the slain flies. Silkworms are liable to many diseases; and, even before 1853, a peculiar epizootic, frequently accompanied by the appearance of dark spots upon the skin (whence the name of ”Pebrine” which it has received), had been noted for its mortality. But in the years following 1853 this malady broke out with such extreme violence, that, in 1858, the silk-crop was reduced to a third of the amount which it had reached in 1853; and, up till within the last year or two, it has never attained half the yield of 1853. This means not only that the great number of people engaged in silk growing are some thirty millions sterling poorer than they might have been; it means not only that high prices have had to be paid for imported silkworm eggs, and that, after investing his money in them, in paying for mulberry-leaves and for attendance, the cultivator has constantly seen his silkworms perish and himself plunged in ruin; but it means that the looms of Lyons have lacked employment, and that, for years, enforced idleness and misery have been the portion of a vast population which, in former days, was industrious and well-to-do.

In reading the Report made by M. de Quatref.a.ges in 1859, it is exceedingly interesting to observe that his elaborate study of the Pebrine forced the conviction upon his mind that, in its mode of occurrence and propagation, the disease of the silkworm is, in every respect, comparable to the cholera among mankind. But it differs from the cholera, and so far is a more formidable malady, in being hereditary, and in being, under some circ.u.mstances, contagious as well as infectious.

The Italian naturalist, Filippi, discovered in the blood of the silkworms affected by this strange disorder a mult.i.tude of cylindrical corpuscles, each about 1/6000th of an inch long. These have been carefully studied by Lebert, and named by him _Panhistophyton_; for the reason that in subjects in which the disease is strongly developed, the corpuscles swarm in every tissue and organ of the body, and even pa.s.s into the undeveloped eggs of the female moth. But are these corpuscles causes, or mere concomitants, of the disease? Some naturalists took one view and some another; and it was not until the French Government, alarmed by the continued ravages of the malady, and the inefficiency of the remedies which had been suggested, despatched M. Pasteur to study it, that the question received its final settlement; at a great sacrifice, not only of the time and peace of mind of that eminent philosopher, but, I regret to have to add, of his health.

But the sacrifice has not been in vain. It is now certain that this devastating, cholera-like Pebrine is the effect of the growth and multiplication of the _Panhistophyton_ in the silkworm. It is contagious and infectious, because the corpuscles of the _Panhistophyton_ pa.s.s away from the bodies of the diseased caterpillars, directly or indirectly, to the alimentary ca.n.a.l of healthy silkworms in their neighbourhood; it is hereditary because the corpuscles enter into the eggs while they are being formed, and consequently are carried within them when they are laid; and for this reason, also? it presents the very singular peculiarity of being inherited only on the mother's side. There is not a single one of all the apparently capricious and unaccountable phenomena presented by the Pebrine, but has received its explanation from the fact that the disease is the result of the presence of the microscopic organism, _Panhistophyton_.

CCXXII

I commenced this Address by asking you to follow me in an attempt to trace the path which has been followed by a scientific idea, in its long and slow progress from the position of a probable hypothesis to that of an established law of nature. Our survey has not taken us into very attractive regions; it has lain, chiefly, in a land flowing with the abominable, and peopled with mere grubs and mouldiness. And it may be imagined with what smiles and shrugs, practical and serious contemporaries of Redi and of Spallanzani may have commented on the waste of their high abilities in toiling at the solution of problems which, though curious enough in themselves, could be of no conceivable utility to mankind.

Nevertheless, you will have observed that before we had travelled very far upon our road, there appeared, on the right hand and on the left, fields laden with a harvest of golden grain, immediately convertible into those things which the most solidly practical men will admit to have value--viz., money and life.

The direct loss to France caused by the Pebrine in seventeen years cannot be estimated at less than fifty millions sterling; and if we add to this what Redi's idea, in Pasteur's hands, has done for the wine-grower and for the vinegar-maker; and try to capitalise its value, we shall find that it will go a long way towards repairing; the money losses caused by the frightful and calamitous war of this autumn (1870). And as to the equivalent of Redi's thought in life, how can we overestimate the value of that knowledge of the nature of epidemic and epizootic diseases, and consequently of the means of checking, or eradicating them, the dawn of which has a.s.suredly commenced?

Looking back no further than ten years, it is possible to select three (1863, 1864, and 1869) in which the total number of deaths from scarlet-fever alone amounted to ninety thousand. That is the return of killed, the maimed and disabled being left out of sight Why, it is to be hoped that the list of killed in the present bloodiest of all wars will not amount to more than this! But the facts which I have placed before you must leave the least sanguine without a doubt that the nature and the causes of this scourge will, one day, be as well understood as those of the Pebrine are now; and that the long-suffered ma.s.sacre of our innocents will come to an end.

And thus mankind will have one more admonition that ”the people perish for lack of knowledge”; and that the alleviation of the miseries, and the promotion of the welfare, of men must be sought, by those who will not lose their pains, in that diligent, patient, loving study of all the mult.i.tudinous aspects of Nature, the results of which const.i.tute exact knowledge, or Science.

CCXXIII

I find three, more or less contradictory, systems of geological thought, each of which might fairly enough claim these appellations, standing side by side in Britain. I shall call one of them Catastrophisim another Uniformitarianism, the third Evolutionism; and I shall try briefly to sketch the characters of each, that you may say whether the cla.s.sification is, or is not, exhaustive.

By Catastrophism I mean any form of geological speculation which, in order to account for the phenomena of geology supposes the operation of forces different in their nature, or immeasurably different in power, from those which we at present see in action in the universe.

The Mosaic cosmogony is, in this sense, catastrophic, because it a.s.sumes the operation of extra-natural power. The doctrine of violent upheavals, _debacles_ and cataclysms in general, is catastrophic, so far as it a.s.sumes that these were brought about by causes which have now no parallel. There was a time when catastrophism might, pre-eminently, have claimed the t.i.tle of ”British popular geology”; and a.s.suredly it has yet many adherents, and reckons among its supporters some of the most honoured members of this Society.

By Uniformitarianism I mean especially the teaching of Hutton and of Lyell.

That great though incomplete work, ”The Theory of the Earth”, seems to me to be one of the most remarkable contributions to geology which is recorded in the annals of the science. So far as the not-living world is concerned, uniformitarianism lies there, not only in germ, but in blossom and fruit.

If one asks how it is that Hutton was led to entertain views so far in advance of those prevalent in his time, in some respects; while, in others, they seem almost curiously limited, the answer appears to me to be plain.

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