Part 27 (1/2)
Amphetamine Unlikely C.
As...o...b..c acid (vitamin C) None A*
Beta-carotene Low dose: none C.
Calcium salts Unlikely NA.
Chlorpromazine Unlikely C.
Cimetidine Unlikely B.
Cisapride Undetermined C.
Cyanocobalamin Undetermined NA.
Dexfenfluramine Undetermined C.
Diethylpropion None NA.
Famotidine Unlikely B.
Fenfluramine Undetermined NA.
Folic acid None A*
Iron None NA.
Isotretinoin High Xm Mazindol Undetermined NA.
Methamphetamine Unlikely (therapeutic dose) NA.
Metoclopromide Unlikely B.
Niacin Undetermined A*
Nizatidine Undetermined B.
Omeprazole Unlikely C.
Pantothenate Undetermined NA.
Phendimetrazine Unlikely NA.
Phentermine Undetermined C.
Prochlorperazine None NA.
Promethazine None C.
Pyridoxine None A.
Ranitidine Unlikely B.
Retinol (vitamin A) Low dose: none A*
High dose: undetermined Thiamine Undetermined A*
Vitamin D Unlikely A*
Vitamin E Undetermined A*
NA, not available.
Compiled from: Friedman et al., Obstet Gynecol 1990; 75 75: 594; Briggs et al., 2005; Friedman and Polifka, 2006.
gastric acid reflux. Therapy consists primarily of one of the antacid preparations discussed in the previous section. Frequent small feedings and elevation of the head of the bed at night may be beneficial. An H -receptor antagonist or omeprazole, as well as 2 metoclopramide, may also prove useful for severe forms of reflux. Esomeperazole and omeprazole are the most popular treatments for reflux esophagitis, and omeprazole is well studied during pregnancy.
Special considerations 237.
Box 12.4 Therapy for nausea and vomiting of pregnancya Chlorpramazine Chlorpramazine *
Suppositories, 50100 mg q 8 h *
Oral, 1025 mg q 4 h *
Parenteral, 12.525 mg IM q 4 h Ondansetron *
Intravenous, 32 mg as a single dose once a day *
Oral, 8 mg bid Prochlorperazine *
Suppositories, 510 mg two to three times per day *
Oral, 510 mg tid or gid *
Parenteral, 510 mg IM q 4 h Promethazine *
Suppositories, 12.525 mg q 4 h *
Oral, 510 mg tid or gid *
Parenteral, 25 mg IM q 4 h Thiethylperazine *
Suppositories, 10 mg gd to tid *
Oral, 10 mg qd to tid *
Parenteral, 10 mg IM qd to tid Trimethobenzamide *
Suppositories, 200 mg tid or gid *