Part 8 (1/2)
As a parallel to this, it may be stated, that, as regards either endemic or epidemic disease, those persons newly arrived, either in a district or country where these prevail, are even more liable to them than the residents.[63] Again, I have learned, that where the potato disease has been so bad as to render the crop almost valueless, the best plan to be adopted is, to allow the plants to remain in the earth, and thus leave such as retain their germinating powers to come up spontaneously the following year. I certainly saw one large field treated in this way, yield a crop almost without disease.
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The seasoning, in this instance, seems to bear a comparison with the seasoning of animals and man, under a variety of diseases, which for a time renders them insusceptible of another attack. It therefore does not appear so improbable, that these affections may be regarded, as Unger, the German botanist supposed, the Exanthemata, or Eruptive Fevers of vegetables.
Another feature seems to a.s.sociate the Epidemics of plants and animals, in a manner suggestive of a.n.a.logous causes operating in both instances.
The lungs of animals and the leaves of vegetables, are their respiratory organs, by means of which, the blood in the one case and the sap in the other, derive gas from the air, and impart gas to it, each taking what is thrown off by the other.
Now the epidemics among vegetables, have a remarkable tendency to exhibit their effects primarily on the leaves, and particularly on those parts which are appropriated to the function of respiration. It is from the stomates that many of the fungi commence to germinate, and their fructification may be seen sprouting from the opening composed of a c.h.i.n.k, surrounded by a peculiar arrangement of cells, which const.i.tute the breathing apparatus of their victim.
In the earlier epidemics, of which we read, one of the most remarkable circ.u.mstances, was the extraordinary influence the poisonous matter appeared to {161} exercise over the lungs,[64] and they again, were the means of propagating the disease, and spreading the contagious particles through the atmosphere, for we read: ”Thus did the plague rage in Avignon for six or eight weeks, and the pestilential breath of the sick, who expectorated blood, caused a terrible contagion far and near, for even the vicinity of those who had fallen ill of plague was certain death; so that parents abandoned their infected children, and all the ties of kindred were dissolved.”[65] ”The like was seen in Egypt. Here also inflammation of the lungs was predominant.” ”Here too the _breath_ of the sick spread a deadly contagion.”
It is more than probable that all infectious matter obtains an entrance to the system through the lungs. Inspiring the air containing the pestilential semina is, indeed, the only plausible explanation of infection; for though the skin is indubitably an absorbing {162} surface, and capable of taking up and conveying to the blood any noxious matter applied to it, yet it is far more probable that the lungs would effect this process with greater rapidity. Then the stomach, the only other absorbing surface to which extraneous matter can be applied, is not likely to be the part where the elements of disease would obtain an entrance to the system, for many facts prove, that infectious matter may be swallowed without any injurious consequences, unless in a very concentrated state. Instances are not easily found of diseased matter having been swallowed, except where diseased vegetables have formed under some combination of circ.u.mstances, a portion of diet.[66]
Many facts are on record which prove the powerful effect of diseased grain when made into bread, and taken for any length time as a princ.i.p.al article of food. The history of Ergot of Rye is too fresh in the memory of most people to require more than an allusion here. The stomach had no power over the secale, its poisonous properties were retained, after having been submitted to the digestive process, as was evidenced by the abortions and gangrenes it occasioned.
But diseased wheat is also capable of inducing {163} gangrene, and it is more than probable, that many diseases might be traced to the use of infected grain of various kinds. An interesting account of a family who lived at Wattisham, near Stowmarket, in Suffolk, and all of whom suffered more or less from living on bread made of s.m.u.tty wheat, may be found in the Philosophical Transactions. The mother of this family and five of the children, consisting of three girls and two boys, all suffered from gangrene of the extremities; the father lost the nails from his hands, and had ulceration of two of his fingers.[67] Dr. Woollaston wrote thus in a letter on this case: ”The corn with which they made their bread was certainly very bad: it was wheat that had been cut in a rainy season, and had lain on the ground till many of the grains were black and totally decayed, but many other poor families in the same village made use of the same corn without receiving any injury from it. One man lost the use of his arm for some time, and still imagines himself that he was afflicted with the same disorder as Downing's family.” It is not unlikely this was the case, for numbness and loss of power was one of the well marked characters of the disease.
What other afflictions may be due to diseased vegetation and adulterated articles of food, and what loss of life may accrue from cheap and adulterated {164} drugs and chemicals is hardly yet dreamt of.[68] The systematic practice of adulteration of almost every article of diet which comes to table has become a serious question for the legislature to consider. Take only the article of milk, upon which the young children of large towns and cities, make their chief meals, with the addition of bread.
How much milk comes into London from the country, how much is obtained from stall and grain-fed cows in the metropolis, and how much is said to be consumed, would be an interesting calculation. It is pretty well known that a mixture is sold by which a retailer of milk may increase his supply by one-third or one-half. It was discovered in Paris that the brains of animals, when prepared in a particular manner, formed, when mixed with a certain proportion of milk and water, a very fine and deceptive cream; in that city this system was carried on to a considerable extent. I could not help alluding to these facts while speaking of diseased grain, for who shall say to what extent a miller in a large way of business, may be able to ”work in,” as it is called, a considerable amount of s.m.u.tty corn in the manufacture of flour? Now, as diseased grain is known {165} to induce abortion, it is impossible to tell how small a portion may in some cases produce the effect; we may therefore say with Thomas of Malmesbury, ”There is no action of man in this life which is not the beginning of so long a chain of consequences, as that no human providence is high enough to give us a prospect to the end.”[69]
To return,--a.s.sociated with these observations are other facts of considerable weight. Before and during pestilences, abortions are more frequent than in ordinary times; infectious and contagious diseases induce abortion; besides this, and independently of disease, conditions of the atmosphere have been known to exist when abortion has been an epidemic affection; of this Dr. Copland says, ”to certain states of the atmosphere only can be attributed those frequent abortions sometimes observed which have even a.s.sumed an epidemic form, and of which Hippocrates, Fischer, Tessier, Desormeaux, and others have made mention.” With this reference I will close the subject of comparison between the affections of the breathing apparatus in animals and plants, merely alluding to the probability that under some conditions of atmosphere, independently of heat, &c. vegetables without any other a.s.signable cause will become abortive.
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SECTION II.
WHAT IS THE NATURE OF THOSE POISONS WHICH MOST RESEMBLE THE MORBID POISONS IN THEIR EFFECTS ON THE BODY?
In the early part of this book, I considered the nature of poisons generally, and had occasion to remark upon the characters which separated poisons into two distinct cla.s.ses. 1st, Those which have the power of self multiplication; and 2nd, Those dest.i.tute of this property.
Of the first we have seen that the poisons of epidemic diseases multiply both in and out of the body.
The poisons of infectious diseases, not usually epidemic, do the same.
Those of endemic affections, such as ague and some fevers, usually become multiplied out of the body only, but under some circ.u.mstances, and peculiar atmospheric conditions, they may be also multiplied within the body. The amount of these poisons necessary to produce their specific effects, may be inappreciable. Of the second cla.s.s, there are two kinds, those derived from the organic kingdom and those derived from the inorganic kingdom. Of these, the amount necessary to produce their specific effects is appreciable and pretty well known.
But among those poisons, consisting of organic {167} products, there is one which seems to hold an intermediate place. This is derived from one of the Fungals, and as it takes this remarkable position as a link of connexion between the two cla.s.ses of poisons, I may be excused quoting a pa.s.sage of some length upon this agent, from Dr. Lindley's Vegetable Kingdom. ”One of the most poisonous of our fungi, is the Amanita muscaria, so called from its power of killing flies, when steeped in milk. Even this is eaten in Kamchatka, with no other than intoxicating effects, according to the following account by Langsdorf, as translated by Greville. This variety of Amanita muscaria, is used by the inhabitants of the north-eastern parts of Asia in the same manner as wine, brandy, arrack, opium, &c. is by other nations.”--”The most singular effect of the amanita is the influence it possesses over the urine. It is said, that from time immemorial, the inhabitants have known that the fungus imparts an intoxicating quality to that secretion, which _continues for a considerable time after taking it_.
For instance, a man moderately intoxicated to-day, will by the next morning have slept himself sober, but (as is the custom) by taking a teacup of his urine, he will be _more powerfully intoxicated_ than he was the preceding day. It is, therefore, not uncommon for confirmed drunkards to preserve their urine, as a precious liquor against a scarcity of the fungus. The intoxicating property of the urine _is capable of_ {168} _being propagated_; for every one who partakes of it has his urine similarly affected. Thus with a very few amanitae, a party of drunkards may keep up their debauch for a week.”
This property of the amanita, at once places it in a separate category from all other organic poisons, it has yet to be shewn upon what this intoxicating fungus depends for its activity. Whether some secretion is formed in the tissue of the plant, or whether some new arrangement of the particles of matter or modification of the sporules, is brought about by entering the system, it is impossible to say. Langsdorf states that the small deep-coloured specimens of amanita, and thickly covered with warts, are said to be more powerful than those of a larger size and paler colour.
As the effect is not produced until from one to two hours after swallowing the bolus, and as a pleasant intoxication may be obtained by this agent for a whole day, and from one dose only, there is a defined line between this and the ordinary narcotics and stimulants in common use. That the digestive powers of the stomach have no influence over the intoxicating properties of the plant, is manifested in the fact, that the active principle pa.s.ses into the urine, not only not deteriorated but apparently increased, for, as we have seen, a teacup of the urine from a man, intoxicated by taking the amanita into his stomach, will cause him to be more powerfully intoxicated than by the {169} original dose. We have, therefore, but two conjectures left for consideration, either the original intoxicating principle is excreted from the system in a condensed form, in which case its indestructibility by digestion, makes it approach the ordinary organic poisons, or there must be an increase of the toxic agent, in which case we must suppose a reproductive process having taken place in the system.
”There is,” says Dr. Mitch.e.l.l, ”in the wild regions of our western country, a disease called the _milk sickness_, the _trembles_, the _tires_, the _slows_, the _stiff-joints_, the _puking fever_, _&c._” The animals affected with this disease, ”stray irregularly, apparently without motive;”
they lose their power of attention, and finally tremble, stagger, and die.
”When other animals--men, dogs, cats, poultry, crows, buzzards, and hogs, drink the milk or eat the flesh of a diseased cow, they suffer in a somewhat similar manner.” This disease is attributed by Dr. Mitch.e.l.l to the animals having grazed on pasture contaminated with mildew, and the resemblance to the effects of the amanita, together with the persistence of the specific principle within the fluids and tissues of the body, render it more than probable that to some fungoid growth, is due the peculiar toxic effects here noticed. Further: ”The animals made sick by the beef of the first one, have been in their turn the cause of a like affection in others; so that three or four have thus fallen victims successively.” De Graaf states, that b.u.t.ter {170} made from the milk of diseased cows, though heated until it caught fire, did not lose its deleterious properties. The urine of diseased animals, collected and reduced by evaporation, produced the characteristic symptoms. All these facts point to some peculiarity in the properties of matter not yet investigated or at least not explained. If we may a.s.sume that reproduction is here an element of the persistence and apparent multiplication of active matter, I know only of one instance to compare with it. A gentleman about to deliver a lecture on the properties of a.r.s.enic, and its history generally, made two solutions of a given quant.i.ty of a.r.s.enious acid, in the following manner. He took a certain amount of distilled water, and the same of filtered Thames water, and made his solutions of a.r.s.enic by separate boilings, he then as soon as possible placed the liquids in identical bottles, carefully prepared for their reception. In the one which contained the a.r.s.enic boiled in river water, the hygrocrocis is now growing, while that boiled in distilled water remains perfectly limpid and free from any vegetable production. There can scarcely be a doubt, that the filtration of river water was not sufficiently purifying to remove the minute spores of some lower forms of vegetation, which not only live in a.r.s.enic but have resisted the temperature employed in boiling an a.r.s.enical solution to saturation.