Chapter 722 (1/2)

”Let's sort out the existing data first.” Guo Xiang said.

”I have data here.” Li Yuanhang handed a floppy disk.

Guo Xiang turns on a computer brought back by Li Yuanhang and prepares to use it.

This computer uses Windows 3.0 system, which is much easier to use than the domestic DOS system.

Moreover, the computer is all in English. It is relatively difficult to operate, but it is also safer. It will not be easy to be used by others.

Domestic computers will be reserved for others in the future, and some students may be recruited at that time.

Insert the floppy disk into the floppy disk slot to read data.

The data are complete, mainly the virus data and current drugs studied by Dr. Hua.

”Can I use this?” Guo Xiang is a little worried.

”Yes, with the permission of Mr. Hua, and many drugs are available on the market and used in clinic. They can be collected if you want to collect them.” Li Yuanhang said.

”That's good!” Guo Xiang copied the data on his computer.

There are four main categories of drugs.

Nucleoside reverse transcriptase inhibitor (NRTI): the molecular structure of this drug is similar to that of natural deoxynucleotides. It can be added to the DNA chain instead of deoxynucleotides to terminate DNA synthesis. Zidovudine, lamivudine, tenofovir and ntriptabine all belong to this class of drugs.

Non nucleoside reverse transcriptase inhibitor (NNRTI): the molecular structure of this drug is completely different from that of nucleoside. It is combined with other parts of reverse transcriptase, making the reverse transcription process impossible. Nevirapine and efavirin belong to this class of drugs.

Protease inhibitor (PI): combined with protease to inhibit protease activity.

Integrase inhibitor (insi): combined with integrase to inhibit integrase activity.

”Now we mainly use three kinds of antiretroviral drugs to treat AIDS, like cocktails mixing different wines, we call it cocktail therapy.” Guo Xiang said.

”Cocktail therapy? It's a little interesting! ” Li Yuanhang nodded, ”you are very creative.”

Guo Xiang smiled guilty. In fact, this was put forward by Dr. Hua Hongmin in his previous life. He just borrowed it in advance, but how to dispense the medicine still needs a lot of experiments.

At that time, if you can really succeed, write Dr. Hua's name in front of you. You don't dare to monopolize the credit.

”These three drugs are not randomly matched. They must contain two nucleoside reverse transcriptase inhibitors and one other type of drug. In this way, the problem of drug resistance of single drug can be overcome. ” Guo Xiang continued.

”You're right.” Li Yuanhang nodded, ”now we have more than a dozen drugs here. Which two nucleoside drugs are matched with the other, and how much the ratio is, we have to go through many experiments to know. It's not just a few times. ”

”That's natural. It's not that easy.” Guo Xiang nodded and made an approximate drug type ratio on the computer.

Li Yuanhang was very curious when he saw her make a chart. In the chart, all types of drugs are matched with other drugs respectively. At that time, just experiment one by one according to this.

”What is this?” Li Yuanhang was surprised. This watch is well done.

”This is a mind map.” Guo Xiang Xiaoxiao, this is widely used in later generations, and she often uses it. It can be used in all fields and is easy to use.

”At a glance, clear, very good.” Li Yuanhang praised.

”Thank you.” Guo Xiang smiled, ”if you want to learn, I can teach you.”